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Gene: Tymp (thymidine phosphorylase) Rattus norvegicus
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Symbol: Tymp
Name: thymidine phosphorylase
Description: Predicted to have protein homodimerization activity and thymidine phosphorylase activity. Predicted to be involved in several processes, including regulation of gastric motility; regulation of myelination; and regulation of transmission of nerve impulse. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; mitochondrial DNA depletion syndrome 1; mitochondrial encephalomyopathy; pancreatic cancer; and transitional cell carcinoma. Orthologous to human TYMP (thymidine phosphorylase); PARTICIPATES IN beta-ureidopropionase deficiency pathway; capecitabine pharmacodynamics pathway; capecitabine pharmacokinetics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ecgf1; endothelial cell growth factor 1 (platelet-derived); LOC315219; MGC108801; MGC112734; tdRPase; TP
Orthologs:
Homo sapiens (human) : TYMP (thymidine phosphorylase)  HGNC  Alliance
Mus musculus (house mouse) : Tymp (thymidine phosphorylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tymp (thymidine phosphorylase)
Pan paniscus (bonobo/pygmy chimpanzee) : TYMP (thymidine phosphorylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tymp (thymidine phosphorylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07130,342,481 - 130,347,845 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07130,027,662 - 130,033,050 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,666,518 - 127,671,624 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17127,700,749 - 127,705,854 (-)NCBI
Celera7116,911,732 - 116,916,838 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tymp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305756
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.