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Gene: Casp8ap2 (caspase 8 associated protein 2) Rattus norvegicus
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Symbol: Casp8ap2
Name: caspase 8 associated protein 2
Description: Predicted to have several functions, including SUMO polymer binding activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and transcription corepressor activity. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process; cell surface receptor signaling pathway; and cellular response to mechanical stimulus. Localizes to the cytoplasm and nucleus. Orthologous to human CASP8AP2 (caspase 8 associated protein 2); PARTICIPATES IN aldosterone signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CASP8-associated protein 2; LOC313128
Orthologs:
Homo sapiens (human) : CASP8AP2 (caspase 8 associated protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Casp8ap2 (caspase 8 associated protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp8ap2 (caspase 8 associated protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP8AP2 (caspase 8 associated protein 2)
Canis lupus familiaris (dog) : CASP8AP2 (caspase 8 associated protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp8ap2 (caspase 8 associated protein 2)
Sus scrofa (pig) : CASP8AP2 (caspase 8 associated protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0547,853,699 - 47,891,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0552,451,775 - 52,489,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,920,175 - 48,958,139 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1548,928,473 - 49,096,830 (+)NCBI
Celera545,775,811 - 45,813,420 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Casp8ap2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305771
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.