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Gene: Trim21 (tripartite motif-containing 21) Rattus norvegicus
Symbol: Trim21
Name: tripartite motif-containing 21
Description: Predicted to have protein homodimerization activity; protein kinase binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of viral process; protein ubiquitination; and regulation of DNA-binding transcription factor activity. Predicted to colocalize with SCF ubiquitin ligase complex. Orthologous to human TRIM21 (tripartite motif containing 21); PARTICIPATES IN systemic lupus erythematosus pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: INFERRED
Also known as: 52 kDa Ro protein; E3 ubiquitin-protein ligase TRIM21; LOC308901; tripartite motif protein 21
Homo sapiens (human) : TRIM21 (tripartite motif containing 21)  HGNC  Alliance
Mus musculus (house mouse) : Trim21 (tripartite motif-containing 21)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trim21 (tripartite motif containing 21)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIM21 (tripartite motif containing 21)
Canis lupus familiaris (dog) : TRIM21 (tripartite motif containing 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trim21 (tripartite motif containing 21)
Sus scrofa (pig) : TRIM21 (tripartite motif containing 21)
Chlorocebus sabaeus (African green monkey) : TRIM21 (tripartite motif containing 21)
Heterocephalus glaber (naked mole-rat) : Trim21 (tripartite motif containing 21)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01167,686,148 - 167,708,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1167,686,173 - 167,708,714 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,871,557 - 173,894,155 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41160,175,882 - 160,187,661 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11160,254,898 - 160,276,114 (-)NCBI
Celera1155,032,978 - 155,043,976 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Trim21
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305795
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.