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Gene: Mylk3 (myosin light chain kinase 3) Rattus norvegicus
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Symbol: Mylk3
Name: myosin light chain kinase 3
Description: Exhibits calmodulin-dependent protein kinase activity and myosin light chain kinase activity. Involved in myofibril assembly; positive regulation of sarcomere organization; and protein phosphorylation. Localizes to the cytosol. Predicted to colocalize with the actin cytoskeleton. Orthologous to human MYLK3 (myosin light chain kinase 3); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH acrylamide; bisphenol A; manganese(II) chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cardiac-MLCK; cardiac-MyBP-C-associated Ca/CaM kinase; LOC291926; MLCK; putative myosin light chain kinase 3; RGD1305801; similar to Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2)
Orthologs:
Homo sapiens (human) : MYLK3 (myosin light chain kinase 3)  HGNC  Alliance
Mus musculus (house mouse) : Mylk3 (myosin light chain kinase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mylk3 (myosin light chain kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MYLK3 (myosin light chain kinase 3)
Canis lupus familiaris (dog) : MYLK3 (myosin light chain kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mylk3 (myosin light chain kinase 3)
Sus scrofa (pig) : MYLK3 (myosin light chain kinase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01927,388,163 - 27,442,451 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1927,404,712 - 27,441,536 (+)Ensembl
Rnor_5.01938,356,781 - 38,408,247 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41923,068,059 - 23,101,629 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11923,072,884 - 23,120,712 (+)NCBI
Celera1921,568,596 - 21,602,349 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mylk3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305801
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.