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Gene: Sirt7 (sirtuin 7) Rattus norvegicus
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Symbol: Sirt7
Name: sirtuin 7
Description: Predicted to have NAD-dependent histone deacetylase activity (H3-K18 specific) and chromatin binding activity. Predicted to be involved in histone H3 deacetylation; rRNA transcription; and regulation of transcription, DNA-templated. Predicted to localize to the nuclear telomeric heterochromatin and nucleolus organizer region. Orthologous to human SIRT7 (sirtuin 7); PARTICIPATES IN histone modification pathway; RNA polymerase I transcription pathway; Sirtuin mediated pathway; INTERACTS WITH bisphenol A; thioacetamide; vinclozolin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC303745; NAD-dependent deacetylase sirtuin-7; NAD-dependent protein deacetylase sirtuin-7; regulatory protein SIR2 homolog 7; SIR2-like protein 7; sirtuin 7 (silent mating type information regulation 2, homolog) 7 (S. cerevisiae)
Orthologs:
Homo sapiens (human) : SIRT7 (sirtuin 7)  HGNC  Alliance
Mus musculus (house mouse) : Sirt7 (sirtuin 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sirt7 (sirtuin 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SIRT7 (sirtuin 7)
Canis lupus familiaris (dog) : SIRT7 (sirtuin 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sirt7 (sirtuin 7)
Sus scrofa (pig) : SIRT7 (sirtuin 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010109,796,046 - 109,802,821 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010109,389,098 - 109,395,852 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410110,009,669 - 110,016,346 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110110,024,660 - 110,030,830 (-)NCBI
Celera10104,439,874 - 104,446,570 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sirt7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305876
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.