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Gene: Sirt7 (sirtuin 7) Rattus norvegicus
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Symbol: Sirt7
Name: sirtuin 7
CRRD ID: 1305876
Description: Predicted to have several functions, including hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; protein-propionyllysine depropionylase activity; and transcription corepressor activity. Predicted to be involved in several processes, including cellular macromolecule biosynthetic process; protein deacylation; and regulation of nucleobase-containing compound metabolic process. Predicted to localize to nucleolus organizer region; nucleoplasm; and site of double-strand break. Orthologous to human SIRT7 (sirtuin 7); PARTICIPATES IN histone modification pathway; RNA polymerase I transcription pathway; Sirtuin mediated pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; bisphenol A; cadmium atom.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC303745; NAD-dependent deacetylase sirtuin-7; NAD-dependent protein deacetylase sirtuin-7; NAD-dependent protein deacylase sirtuin-7; regulatory protein SIR2 homolog 7; SIR2-like protein 7; sirtuin 7 (silent mating type information regulation 2, homolog) 7 (S. cerevisiae)
Orthologs:
Homo sapiens (human) : SIRT7 (sirtuin 7)  HGNC  Alliance
Mus musculus (house mouse) : Sirt7 (sirtuin 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sirt7 (sirtuin 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SIRT7 (sirtuin 7)
Canis lupus familiaris (dog) : SIRT7 (sirtuin 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sirt7 (sirtuin 7)
Sus scrofa (pig) : SIRT7 (sirtuin 7)
Chlorocebus sabaeus (African green monkey) : SIRT7 (sirtuin 7)
Heterocephalus glaber (naked mole-rat) : Sirt7 (sirtuin 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010109,796,046 - 109,802,821 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,796,020 - 109,802,739 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,389,098 - 109,395,852 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410110,009,669 - 110,016,346 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110110,024,660 - 110,030,830 (-)NCBI
Celera10104,439,874 - 104,446,570 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sirt7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305876
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.