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Gene: Tcf7 (transcription factor 7) Rattus norvegicus
Symbol: Tcf7
Name: transcription factor 7
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and beta-catenin binding activity. Predicted to be involved in several processes, including T cell differentiation; canonical Wnt signaling pathway involved in negative regulation of apoptotic process; and embryonic morphogenesis. Predicted to localize to nuclear body; nuclear euchromatin; and transcription factor complex. Orthologous to human TCF7 (transcription factor 7); PARTICIPATES IN Wnt signaling, canonical pathway; acute myeloid leukemia pathway; arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH amphetamine; cisplatin; diazinon.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC363595; transcription factor 7 (T-cell specific, HMG-box); transcription factor 7, T-cell specific
Homo sapiens (human) : TCF7 (transcription factor 7)  HGNC  Alliance
Mus musculus (house mouse) : Tcf7 (transcription factor 7, T cell specific)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tcf7 (transcription factor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : TCF7 (transcription factor 7)
Canis lupus familiaris (dog) : TCF7 (transcription factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcf7 (transcription factor 7)
Sus scrofa (pig) : TCF7 (transcription factor 7)
Chlorocebus sabaeus (African green monkey) : TCF7 (transcription factor 7)
Heterocephalus glaber (naked mole-rat) : Tcf7 (transcription factor 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01037,616,033 - 37,646,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,617,279 - 37,645,802 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01037,389,506 - 37,419,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,686,862 - 37,716,831 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11037,693,621 - 37,723,030 (-)NCBI
Celera1035,778,033 - 35,807,975 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tcf7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305894
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.