Gene: Tcf7 (transcription factor 7) Rattus norvegicus
Symbol: Tcf7
Name: transcription factor 7
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and beta-catenin binding activity; predicted to be involved in several processes, including animal organ development, canonical Wnt signaling pathway involved in negative regulation of apoptotic process, and cellular response to interleukin-4; predicted to localize to the nuclear body, nuclear euchromatin, and transcription factor complex; orthologous to human TCF7 (transcription factor 7); PARTICIPATES IN Wnt signaling, canonical pathway; acute myeloid leukemia pathway; arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; cisplatin.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC363595; transcription factor 7 (T-cell specific, HMG-box); transcription factor 7, T-cell specific
Homo sapiens (human) : TCF7 (transcription factor 7)  HGNC  Alliance
Mus musculus (house mouse) : Tcf7 (transcription factor 7, T cell specific)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tcf7 (transcription factor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : TCF7 (transcription factor 7)
Canis lupus familiaris (dog) : TCF7 (transcription factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcf7 (transcription factor 7)
Sus scrofa (pig) : TCF7 (transcription factor 7 (T-cell specific, HMG-box))
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01037,616,033 - 37,646,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01037,389,506 - 37,419,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,686,862 - 37,716,831 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11037,693,621 - 37,723,030 (-)NCBI
Celera1035,778,033 - 35,807,975 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tcf7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305894
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.