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Gene: Ap1s1 (adaptor related protein complex 1 subunit sigma 1) Rattus norvegicus
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Symbol: Ap1s1
Name: adaptor related protein complex 1 subunit sigma 1
Description: Predicted to have ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular response to misfolded protein; protein monoubiquitination; and proteolysis involved in cellular protein catabolic process. Predicted to localize to Golgi apparatus; nucleus; and terminal bouton. Human ortholog(s) of this gene implicated in MEDNIK syndrome. Orthologous to human AP1S1 (adaptor related protein complex 1 subunit sigma 1); INTERACTS WITH bisphenol A; C60 fullerene; flutamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adaptor protein complex AP-1, sigma 1; adaptor-related protein complex 1, sigma 1 subunit; E2 ubiquitin-conjugating enzyme W; LOC360785; MGC188494; N-terminal E2 ubiquitin-conjugating enzyme; N-terminus-conjugating E2; Ube2w; ubiquitin carrier protein W; ubiquitin-conjugating enzyme E2 W; ubiquitin-protein ligase W
Orthologs:
Homo sapiens (human) : AP1S1 (adaptor related protein complex 1 subunit sigma 1)  HGNC  Alliance
Mus musculus (house mouse) : Ap1s1 (adaptor protein complex AP-1, sigma 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ap1s1 (adaptor related protein complex 1 subunit sigma 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AP1S1 (adaptor related protein complex 1 subunit sigma 1)
Canis lupus familiaris (dog) : AP1S1 (adaptor related protein complex 1 subunit sigma 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ap1s1 (adaptor related protein complex 1 subunit sigma 1)
Sus scrofa (pig) : AP1S1 (adaptor related protein complex 1 subunit sigma 1)
Chlorocebus sabaeus (African green monkey) : AP1S1 (adaptor related protein complex 1 subunit sigma 1)
Heterocephalus glaber (naked mole-rat) : Ap1s1 (adaptor related protein complex 1 subunit sigma 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01222,665,128 - 22,676,079 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,665,112 - 22,676,075 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,677,410 - 24,688,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41220,907,855 - 20,918,301 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11220,897,466 - 20,907,910 (-)NCBI
Celera1221,401,021 - 21,411,455 (+)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ap1s1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305911
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.