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Gene: Tnk2 (tyrosine kinase, non-receptor, 2) Rattus norvegicus
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Symbol: Tnk2
Name: tyrosine kinase, non-receptor, 2
Description: Exhibits protein tyrosine kinase activity. Predicted to be involved in several processes, including peptidyl-tyrosine autophosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; and regulation of clathrin-dependent endocytosis. Predicted to localize to several cellular components, including the Grb2-EGFR complex; cytoplasmic vesicle; and neuron projection. Orthologous to human TNK2 (tyrosine kinase non receptor 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ACK-1; activated CDC42 kinase 1; activated p21cdc42Hs kinase; LOC303882; MGC94214; tyrosine kinase non-receptor protein 2
Orthologs:
Homo sapiens (human) : TNK2 (tyrosine kinase non receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Tnk2 (tyrosine kinase, non-receptor, 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnk2 (tyrosine kinase non receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TNK2 (tyrosine kinase non receptor 2)
Canis lupus familiaris (dog) : TNK2 (tyrosine kinase non receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnk2 (tyrosine kinase non receptor 2)
Sus scrofa (pig) : TNK2 (tyrosine kinase non receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01171,348,726 - 71,388,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01174,431,230 - 74,470,437 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,927,509 - 69,966,854 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11169,985,098 - 70,024,443 (-)NCBI
Celera1167,547,447 - 67,587,473 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tnk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305957
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.