Enox1 (ecto-NOX disulfide-thiol exchanger 1) - Chinchilla Research Resource Database
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Gene: Enox1 (ecto-NOX disulfide-thiol exchanger 1) Rattus norvegicus
Analyze
Symbol: Enox1
Name: ecto-NOX disulfide-thiol exchanger 1
CRRD ID: 1306118
Description: Predicted to have RNA binding activity and oxidoreductase activity. Predicted to be involved in oxidation-reduction process and ultradian rhythm. Predicted to localize to plasma membrane. Orthologous to human ENOX1 (ecto-NOX disulfide-thiol exchanger 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; tetrachloromethane.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC306038; RGD1306118; similar to hypothetical protein FLJ31846
Orthologs:
Homo sapiens (human) : ENOX1 (ecto-NOX disulfide-thiol exchanger 1)  HGNC  Alliance
Mus musculus (house mouse) : Enox1 (ecto-NOX disulfide-thiol exchanger 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Enox1 (ecto-NOX disulfide-thiol exchanger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ENOX1 (ecto-NOX disulfide-thiol exchanger 1)
Canis lupus familiaris (dog) : ENOX1 (ecto-NOX disulfide-thiol exchanger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Enox1 (ecto-NOX disulfide-thiol exchanger 1)
Sus scrofa (pig) : ENOX1 (ecto-NOX disulfide-thiol exchanger 1)
Chlorocebus sabaeus (African green monkey) : ENOX1 (ecto-NOX disulfide-thiol exchanger 1)
Heterocephalus glaber (naked mole-rat) : Enox1 (ecto-NOX disulfide-thiol exchanger 1)
more info ...
Allele / Splice: Enox1Tn(sb-T2/Bart3)2.282Mcwi  
Genetic Models: F344-Enox1Tn(sb-T2/Bart3)2.282Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01559,331,134 - 59,884,512 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1559,678,165 - 59,884,511 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01563,013,519 - 63,564,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41558,555,747 - 58,762,870 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11558,529,976 - 58,778,210 (+)NCBI
Celera1552,128,810 - 52,677,995 (+)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References


Genomics

Comparative Map Data
Enox1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01559,331,134 - 59,884,512 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1559,678,165 - 59,884,511 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01563,013,519 - 63,564,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41558,555,747 - 58,762,870 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11558,529,976 - 58,778,210 (+)NCBI
Celera1552,128,810 - 52,677,995 (+)NCBICelera
Cytogenetic Map15q11NCBI
ENOX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1343,213,518 - 43,786,908 (-)EnsemblGRCh38hg38GRCh38
GRCh381343,213,130 - 43,786,976 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371343,787,335 - 44,361,116 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361342,685,704 - 43,139,655 (-)NCBINCBI36hg18NCBI36
Celera1324,843,864 - 25,417,275 (-)NCBI
Cytogenetic Map13q14.11NCBI
HuRef1324,589,879 - 25,163,216 (-)NCBIHuRef
CHM1_11343,755,216 - 44,328,614 (-)NCBICHM1_1
Enox1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391477,393,790 - 77,959,203 (+)NCBI
GRCm381477,156,248 - 77,721,763 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1477,156,763 - 77,721,760 (+)EnsemblGRCm38mm10GRCm38
MGSCv371477,556,623 - 78,121,214 (+)NCBIGRCm37mm9NCBIm37
MGSCv361475,890,971 - 76,455,562 (+)NCBImm8
Celera1474,659,159 - 75,225,482 (+)NCBICelera
Cytogenetic Map14D3NCBI
Enox1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555181,124,556 - 1,352,203 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555181,124,556 - 1,677,025 (-)NCBIChiLan1.0ChiLan1.0
ENOX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13199,336,885 - 199,480,415 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01324,377,918 - 24,722,036 (-)NCBIMhudiblu_PPA_v0panPan3
ENOX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl227,259,071 - 7,673,453 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1227,093,885 - 7,642,984 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Enox1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936747380,813 - 709,258 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENOX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1123,237,697 - 23,894,727 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11123,234,764 - 23,894,763 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21123,830,914 - 24,285,421 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ENOX1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl321,339,690 - 21,545,310 (-)Ensembl
ChlSab1.1321,339,684 - 21,909,377 (-)NCBI
Enox1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474811,308,948 - 11,887,738 (+)NCBI

Position Markers
D15Rat20  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01559,616,275 - 59,616,425NCBIRnor6.0
Rnor_5.01563,298,793 - 63,298,943UniSTSRnor5.0
RGSC_v3.41558,377,126 - 58,377,276UniSTSRGSC3.4
RGSC_v3.41558,377,066 - 58,377,355RGDRGSC3.4
RGSC_v3.11558,392,906 - 58,393,056RGD
Celera1552,413,673 - 52,413,823UniSTS
Cytogenetic Map15q11UniSTS
RH 3.4 Map15467.1UniSTS
RH 3.4 Map15467.1RGD
SHRSP x BN Map1535.7899UniSTS
SHRSP x BN Map1535.7899RGD
D15Rat123  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01559,651,151 - 59,651,287NCBIRnor6.0
Rnor_5.01563,333,669 - 63,333,805UniSTSRnor5.0
RGSC_v3.41558,412,002 - 58,412,138UniSTSRGSC3.4
RGSC_v3.41558,412,001 - 58,412,138RGDRGSC3.4
RGSC_v3.11558,427,782 - 58,427,918RGD
Celera1552,448,507 - 52,448,643UniSTS
Cytogenetic Map15q11UniSTS
RH 3.4 Map15466.9RGD
RH 3.4 Map15466.9UniSTS
SHRSP x BN Map1535.7498RGD
SHRSP x BN Map1535.7498UniSTS
BE096152  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01559,215,607 - 59,215,775NCBIRnor6.0
Rnor_5.01562,898,033 - 62,898,201UniSTSRnor5.0
RGSC_v3.41558,495,986 - 58,496,154UniSTSRGSC3.4
Celera1552,017,018 - 52,017,186UniSTS
Cytogenetic Map15q11UniSTS
RH 3.4 Map15494.11UniSTS
RH128801  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01559,642,843 - 59,643,025NCBIRnor6.0
Rnor_5.01563,325,361 - 63,325,543UniSTSRnor5.0
RGSC_v3.41558,403,694 - 58,403,876UniSTSRGSC3.4
Celera1552,440,199 - 52,440,381UniSTS
Cytogenetic Map15q11UniSTS
RH 3.4 Map15466.6UniSTS
RH133019  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01559,714,016 - 59,714,197NCBIRnor6.0
Rnor_5.01563,394,442 - 63,394,623UniSTSRnor5.0
RGSC_v3.41558,591,451 - 58,591,632UniSTSRGSC3.4
Celera1552,508,723 - 52,508,904UniSTS
Cytogenetic Map15q11UniSTS
RH 3.4 Map15464.19UniSTS
BE119345  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01559,764,556 - 59,764,764NCBIRnor6.0
Rnor_5.01563,444,982 - 63,445,190UniSTSRnor5.0
RGSC_v3.41558,642,162 - 58,642,370UniSTSRGSC3.4
Celera1552,558,697 - 52,558,905UniSTS
Cytogenetic Map15q11UniSTS
RH 3.4 Map15466.9UniSTS
BF418003  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01559,690,196 - 59,690,316NCBIRnor6.0
Rnor_5.01563,370,622 - 63,370,742UniSTSRnor5.0
RGSC_v3.41558,567,631 - 58,567,751UniSTSRGSC3.4
Celera1552,484,903 - 52,485,023UniSTS
Cytogenetic Map15q11UniSTS
RH 3.4 Map15466.9UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
CRRD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15162301382Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151549236072568189Rat
9590272Scort14Serum corticosterone level QTL 142.780.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)151698090761980907Rat
8694427Bw163Body weight QTL 1634.820.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)151698090761980907Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151724964162249641Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151724964162249641Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151724964162249641Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151809320881255430Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151851391388036354Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1526381041106550657Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1526381041106550657Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1526381041106550657Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152870974173709741Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)153321910189640841Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)153321910189640841Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)153321910189640841Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)153321910189640841Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)153321910189640841Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)153948079762596410Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153974955779033707Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153974955779033707Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154106809486068094Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1543097470106550657Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155752897081263988Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)155965115181255430Rat


Genetic Models
This gene Enox1 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:660
Count of miRNA genes:264
Interacting mature miRNAs:334
Transcripts:ENSRNOT00000073481, ENSRNOT00000074868
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 63 3
Low 3 43 20 12 11 12 8 9 11 35 38 11 8
Below cutoff 32 27 8 27 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008770070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AABR07018467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07018468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07018469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01084031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000074868   ⟹   ENSRNOP00000065000
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1559,678,165 - 59,884,511 (+)Ensembl
RefSeq Acc Id: XM_008770070   ⟹   XP_008768292
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1552,439,781 - 52,677,995 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770072   ⟹   XP_008768294
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1552,439,780 - 52,677,995 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770074   ⟹   XP_008768296
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1552,439,782 - 52,677,995 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770914   ⟹   XP_008769136
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01559,642,425 - 59,884,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770915   ⟹   XP_008769137
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01559,642,424 - 59,884,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770916   ⟹   XP_008769138
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01559,642,426 - 59,884,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599959   ⟹   XP_017455448
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01559,609,147 - 59,884,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599960   ⟹   XP_017455449
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01559,331,134 - 59,884,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017604988   ⟹   XP_017460477
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1552,406,513 - 52,677,995 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017604989   ⟹   XP_017460478
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1552,128,810 - 52,677,995 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_008768292   ⟸   XM_008770070
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008768296   ⟸   XM_008770074
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008768294   ⟸   XM_008770072
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_008769136   ⟸   XM_008770914
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008769138   ⟸   XM_008770916
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008769137   ⟸   XM_008770915
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017460478   ⟸   XM_017604989
- Peptide Label: isoform X10
- UniProtKB: D3ZYM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017460477   ⟸   XM_017604988
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017455449   ⟸   XM_017599960
- Peptide Label: isoform X5
- UniProtKB: D3ZYM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455448   ⟸   XM_017599959
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000065000   ⟸   ENSRNOT00000074868
Protein Domains
RRM

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306118 AgrOrtholog
Ensembl Genes ENSRNOG00000047817 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000065000 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074868 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro ENOX UniProtKB/TrEMBL
  ENOX_RRM UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
NCBI Gene 306038 ENTREZGENE
PANTHER PTHR16001 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen Enox1 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
Transposagen Enox1 Transposagen
UniGene Rn.212211 ENTREZGENE
UniProt D3ZYM3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Enox1  ecto-NOX disulfide-thiol exchanger 1  LOC100363621  hypothetical protein LOC100363621  Data Merged 1643240 APPROVED
2010-05-06 LOC100363621  hypothetical protein LOC100363621      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-07 Enox1  ecto-NOX disulfide-thiol exchanger 1  RGD1306118_predicted  similar to hypothetical protein FLJ31846 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 RGD1306118_predicted  similar to hypothetical protein FLJ31846 (predicted)  LOC684954  similar to CG10948-PC, isoform C  Data Merged 1643240 APPROVED
2006-11-19 LOC684954  similar to CG10948-PC, isoform C      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1306118_predicted  similar to hypothetical protein FLJ31846 (predicted)  LOC306038_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC306038_predicted  similar to hypothetical protein FLJ31846 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL