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Gene: Stub1 (STIP1 homology and U-box containing protein 1) Rattus norvegicus
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Symbol: Stub1
Name: STIP1 homology and U-box containing protein 1
Description: Exhibits chaperone binding activity. Involved in several processes, including cellular response to hypoxia; chaperone-mediated autophagy; and response to ischemia. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 16 and hereditary ataxia. Orthologous to human STUB1 (STIP1 homology and U-box containing protein 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: carboxy terminus of Hsp70-interacting protein; Chip; E3 ubiquitin-protein ligase CHIP; LOC287155; MGC116422; STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
Orthologs:
Homo sapiens (human) : STUB1 (STIP1 homology and U-box containing protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Stub1 (STIP1 homology and U-Box containing protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stub1 (STIP1 homology and U-box containing protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : STUB1 (STIP1 homology and U-box containing protein 1)
Canis lupus familiaris (dog) : STUB1 (STIP1 homology and U-box containing protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stub1 (STIP1 homology and U-box containing protein 1)
Sus scrofa (pig) : STUB1 (STIP1 homology and U-box containing protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01015,197,754 - 15,200,035 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01015,010,697 - 15,012,978 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,096,150 - 15,098,431 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,096,147 - 15,098,378 (-)NCBI
Celera1014,519,707 - 14,521,988 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Stub1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306167
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.