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Gene: Aloxe3 (arachidonate lipoxygenase 3) Rattus norvegicus
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Symbol: Aloxe3
Name: arachidonate lipoxygenase 3
Description: Predicted to have hepoxilin A3 synthase activity and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. Involved in arachidonic acid metabolic process; hepoxilin biosynthetic process; and sensory perception of pain. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1 and autosomal recessive congenital ichthyosis 3. Orthologous to human ALOXE3 (arachidonate lipoxygenase 3); INTERACTS WITH bisphenol A; endosulfan; furan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: e-LOX-3; eLOX-3; epidermal LOX-3; epidermis-type lipoxygenase 3; hydroperoxide isomerase ALOXE3; hydroperoxy icosatetraenoate dehydratase; LOC287424
Orthologs:
Homo sapiens (human) : ALOXE3 (arachidonate lipoxygenase 3)  HGNC  Alliance
Mus musculus (house mouse) : Aloxe3 (arachidonate lipoxygenase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aloxe3 (arachidonate lipoxygenase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ALOXE3 (arachidonate lipoxygenase 3)
Canis lupus familiaris (dog) : ALOXE3 (arachidonate lipoxygenase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aloxe3 (arachidonate lipoxygenase 3)
Sus scrofa (pig) : ALOXE3 (arachidonate lipoxygenase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01055,711,996 - 55,735,915 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01055,455,058 - 55,478,971 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,885,573 - 55,908,641 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11055,905,197 - 55,921,901 (+)NCBI
Celera1052,996,789 - 53,019,740 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Aloxe3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306252
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.