Gene: Espl1 (extra spindle pole bodies like 1, separase) Rattus norvegicus
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Symbol: Espl1
Name: extra spindle pole bodies like 1, separase
Description: Predicted to have cysteine-type endopeptidase activity; predicted to be involved in meiotic spindle organization and nuclear division; predicted to localize to the cytoplasm and intracellular organelle; orthologous to human ESPL1 (extra spindle pole bodies like 1, separase); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle pole bodies homolog 1 (S. cerevisiae); extra spindle poles like 1; extra spindle poles like 1 (S. cerevisiae) ; LOC315330; separin
Orthologs:
Homo sapiens (human) : ESPL1 (extra spindle pole bodies like 1, separase)  HGNC  Alliance
Mus musculus (house mouse) : Espl1 (extra spindle pole bodies 1, separase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Espl1 (extra spindle pole bodies like 1, separase)
Pan paniscus (bonobo/pygmy chimpanzee) : ESPL1 (extra spindle pole bodies like 1, separase)
Canis lupus familiaris (dog) : ESPL1 (extra spindle pole bodies like 1, separase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Espl1 (extra spindle pole bodies like 1, separase)
Sus scrofa (pig) : ESPL1 (extra spindle pole bodies like 1, separase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07143,896,890 - 143,923,868 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07143,153,049 - 143,161,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.07141,692,925 - 141,719,617 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,048,197 - 141,074,383 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17141,126,857 - 141,150,662 (+)NCBI
Celera7129,857,507 - 129,884,392 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Espl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306266
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.