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Gene: Abr (ABR activator of RhoGEF and GTPase) Rattus norvegicus
Symbol: Abr
Name: ABR activator of RhoGEF and GTPase
Description: Predicted to have GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including activation of GTPase activity; negative regulation of blood vessel remodeling; and regulation of vesicle-mediated transport. Localizes to glutamatergic synapse and postsynaptic density, intracellular component. Orthologous to human ABR (ABR activator of RhoGEF and GTPase); INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ABR, RhoGEF and GTPase activating protein; active BCR-related; active BCR-related gene; active breakpoint cluster region-related protein; LOC287537
Homo sapiens (human) : ABR (ABR activator of RhoGEF and GTPase)  HGNC  Alliance
Mus musculus (house mouse) : Abr (active BCR-related gene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abr (ABR activator of RhoGEF and GTPase)
Pan paniscus (bonobo/pygmy chimpanzee) : ABR (ABR activator of RhoGEF and GTPase)
Canis lupus familiaris (dog) : ABR (ABR activator of RhoGEF and GTPase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101976167 (active breakpoint cluster region-related protein)
Sus scrofa (pig) : ABR (ABR activator of RhoGEF and GTPase)
Chlorocebus sabaeus (African green monkey) : ABR (ABR activator of RhoGEF and GTPase)
Heterocephalus glaber (naked mole-rat) : Abr (ABR activator of RhoGEF and GTPase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01064,565,121 - 64,657,079 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1064,567,268 - 64,657,089 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01063,250,866 - 63,449,251 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41067,617,776 - 67,760,961 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11067,631,103 - 67,774,585 (+)NCBI
Celera1060,277,504 - 60,420,210 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Abr
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306279
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.