Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Vav2 (vav guanine nucleotide exchange factor 2) Rattus norvegicus
Analyze
Symbol: Vav2
Name: vav guanine nucleotide exchange factor 2
Description: Predicted to have epidermal growth factor receptor binding activity; guanyl-nucleotide exchange factor activity; and phosphotyrosine residue binding activity. Predicted to be involved in several processes, including lamellipodium assembly; positive regulation of phosphatidylinositol 3-kinase activity; and regulation of GTPase activity. Predicted to localize to the cytoplasm and plasma membrane. Orthologous to human VAV2 (vav guanine nucleotide exchange factor 2); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; erythropoietin signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: guanine nucleotide exchange factor VAV2; LOC296603; vav 2 guanine nucleotide exchange factor; Vav2 oncogene
Orthologs:
Homo sapiens (human) : VAV2 (vav guanine nucleotide exchange factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Vav2 (vav 2 oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vav2 (vav guanine nucleotide exchange factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : VAV2 (vav guanine nucleotide exchange factor 2)
Canis lupus familiaris (dog) : VAV2 (vav guanine nucleotide exchange factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vav2 (vav guanine nucleotide exchange factor 2)
Sus scrofa (pig) : VAV2 (vav guanine nucleotide exchange factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.035,811,504 - 5,976,311 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl35,811,504 - 5,976,244 (-)Ensembl
Rnor_5.0311,173,752 - 11,337,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.436,153,681 - 6,347,676 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.136,155,986 - 6,347,501 (-)NCBI
Celera35,380,148 - 5,548,591 (-)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Vav2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306285
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.