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Gene: Hacd2 (3-hydroxyacyl-CoA dehydratase 2) Rattus norvegicus
Symbol: Hacd2
Name: 3-hydroxyacyl-CoA dehydratase 2
Description: Predicted to have 3-hydroxyacyl-CoA dehydratase activity and enzyme binding activity. Predicted to be involved in fatty acid elongation; sphingolipid biosynthetic process; and very long-chain fatty acid biosynthetic process. Predicted to localize to endoplasmic reticulum and integral component of endoplasmic reticulum membrane. Orthologous to human HACD2 (3-hydroxyacyl-CoA dehydratase 2); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 2,4-dinitrotoluene; buspirone; dibutyl phthalate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC288058; protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b; protein-tyrosine phosphatase-like member B; Ptplb; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2
Homo sapiens (human) : HACD2 (3-hydroxyacyl-CoA dehydratase 2)  HGNC  Alliance
Mus musculus (house mouse) : Hacd2 (3-hydroxyacyl-CoA dehydratase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hacd2 (3-hydroxyacyl-CoA dehydratase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HACD2 (3-hydroxyacyl-CoA dehydratase 2)
Canis lupus familiaris (dog) : HACD2 (3-hydroxyacyl-CoA dehydratase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hacd2 (3-hydroxyacyl-CoA dehydratase 2)
Sus scrofa (pig) : HACD2 (3-hydroxyacyl-CoA dehydratase 2)
Chlorocebus sabaeus (African green monkey) : HACD2 (3-hydroxyacyl-CoA dehydratase 2)
Heterocephalus glaber (naked mole-rat) : Hacd2 (3-hydroxyacyl-CoA dehydratase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01168,893,684 - 68,985,635 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,894,445 - 68,989,988 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,984,627 - 72,076,335 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,489,819 - 67,581,576 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11167,547,407 - 67,639,377 (-)NCBI
Celera1165,126,730 - 65,218,607 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Hacd2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306337
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.