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Gene: Nipbl (NIPBL, cohesin loading factor) Rattus norvegicus
Symbol: Nipbl
Name: NIPBL, cohesin loading factor
Description: Predicted to have several functions, including chromo shadow domain binding activity; histone deacetylase binding activity; and mediator complex binding activity. Predicted to be involved in several processes, including animal organ morphogenesis; regulation of transcription by RNA polymerase II; and sister chromatid cohesion. Predicted to localize to chromatin; cytosol; and nucleus. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 1. Orthologous to human NIPBL (NIPBL cohesin loading factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; atrazine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: delangin; IDN3; Nipped-B homolog; Nipped-B homolog (Drosophila); nipped-B-like protein
Homo sapiens (human) : NIPBL (NIPBL cohesin loading factor)  HGNC  Alliance
Mus musculus (house mouse) : Nipbl (NIPBL cohesin loading factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nipbl (NIPBL cohesin loading factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NIPBL (NIPBL cohesin loading factor)
Canis lupus familiaris (dog) : NIPBL (NIPBL cohesin loading factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nipbl (NIPBL cohesin loading factor)
Sus scrofa (pig) : NIPBL (NIPBL cohesin loading factor)
Chlorocebus sabaeus (African green monkey) : NIPBL (NIPBL cohesin loading factor)
Heterocephalus glaber (naked mole-rat) : Nipbl (NIPBL cohesin loading factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0257,508,830 - 57,676,197 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl257,509,428 - 57,600,820 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0278,992,721 - 79,160,884 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4257,908,828 - 58,099,422 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1257,837,538 - 58,006,254 (-)NCBI
Celera253,014,297 - 53,179,686 (-)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nipbl
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306393
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.