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Gene: Fbxw4 (F-box and WD repeat domain containing 4) Rattus norvegicus
Symbol: Fbxw4
Name: F-box and WD repeat domain containing 4
Description: Predicted to be involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; embryonic digit morphogenesis; and positive regulation of mesenchymal cell proliferation. Predicted to localize to the SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in split hand-foot malformation 3. Orthologous to human FBXW4 (F-box and WD repeat domain containing 4); INTERACTS WITH bisphenol A; flutamide; T-2 Toxin.
Type: protein-coding
Also known as: F-box and WD-40 domain protein 4; F-box/WD repeat-containing protein 4; LOC309444
Homo sapiens (human) : FBXW4 (F-box and WD repeat domain containing 4)  HGNC  Alliance
Mus musculus (house mouse) : Fbxw4 (F-box and WD-40 domain protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw4 (F-box and WD repeat domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW4 (F-box and WD repeat domain containing 4)
Canis lupus familiaris (dog) : FBXW4 (F-box and WD repeat domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw4 (F-box and WD repeat domain containing 4)
Sus scrofa (pig) : FBXW4 (F-box and WD repeat domain containing 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01265,318,526 - 265,420,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01270,474,853 - 270,499,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41250,746,869 - 250,874,460 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11251,007,474 - 251,135,492 (-)NCBI
Celera1240,235,760 - 240,322,798 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Fbxw4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306518
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.