Gene: Pkp2 (plakophilin 2) Rattus norvegicus
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Symbol: Pkp2
Name: plakophilin 2
Description: Predicted to have alpha-catenin binding activity, intermediate filament binding activity, and protein kinase C binding activity; involved in several processes, including adherens junction maintenance, cardiac muscle cell action potential, and gap junction assembly; localizes to the adherens junction and intercalated disc; orthologous to human PKP2 (plakophilin 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC287925; plakophilin-2
Orthologs:
Homo sapiens (human) : PKP2 (plakophilin 2)  HGNC  Alliance
Mus musculus (house mouse) : Pkp2 (plakophilin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pkp2 (plakophilin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PKP2 (plakophilin 2)
Canis lupus familiaris (dog) : PKP2 (plakophilin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pkp2 (plakophilin 2)
Sus scrofa (pig) : PKP2 (plakophilin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01188,912,163 - 88,972,213 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01191,966,047 - 92,031,277 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,553,493 - 86,584,425 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,497,846 - 86,625,018 (+)NCBI
Celera1183,407,295 - 83,471,505 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pkp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306533
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.