Gene: Clic2 (chloride intracellular channel 2) Rattus norvegicus
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Symbol: Clic2
Name: chloride intracellular channel 2
Description: Predicted to have chloride channel activity and glutathione peroxidase activity; predicted to be involved in negative regulation of ryanodine-sensitive calcium-release channel activity, positive regulation of binding activity, and regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; predicted to localize to the cytoplasm and nucleus; orthologous to human CLIC2 (chloride intracellular channel 2); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 3,7-dihydropurine-6-thione; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: chloride intracellular channel protein 2; LOC294141; MGC108828
Orthologs:
Homo sapiens (human) : CLIC2 (chloride intracellular channel 2)  HGNC  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clic2 (chloride intracellular channel 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CLIC2 (chloride intracellular channel 2)
Canis lupus familiaris (dog) : CLIC2 (chloride intracellular channel 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clic2 (chloride intracellular channel 2)
Sus scrofa (pig) : CLIC2 (chloride intracellular channel 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.020295,338 - 310,363 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.020289,420 - 304,445 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42066,518 - 81,543 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12066,517 - 81,536 (+)NCBI
Celera201,021,508 - 1,036,650 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Clic2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306580
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.