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Gene: Trip12 (thyroid hormone receptor interactor 12) Rattus norvegicus
Symbol: Trip12
Name: thyroid hormone receptor interactor 12
Description: Predicted to have thyroid hormone receptor binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; cellular response to DNA damage stimulus; and negative regulation of nitrogen compound metabolic process. Predicted to localize to nuclear speck. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 49. Orthologous to human TRIP12 (thyroid hormone receptor interactor 12); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 ubiquitin-protein ligase TRIP12; gene trap locus 6; Gtl6; HECT-type E3 ubiquitin transferase TRIP12; LOC316575; MGC124674; MGC125132; probable E3 ubiquitin-protein ligase TRIP12; thyroid receptor-interacting protein 12; TR-interacting protein 12; TRIP-12
Homo sapiens (human) : TRIP12 (thyroid hormone receptor interactor 12)  HGNC  Alliance
Mus musculus (house mouse) : Trip12 (thyroid hormone receptor interactor 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trip12 (thyroid hormone receptor interactor 12)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIP12 (thyroid hormone receptor interactor 12)
Canis lupus familiaris (dog) : TRIP12 (thyroid hormone receptor interactor 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trip12 (thyroid hormone receptor interactor 12)
Sus scrofa (pig) : TRIP12 (thyroid hormone receptor interactor 12)
Chlorocebus sabaeus (African green monkey) : TRIP12 (thyroid hormone receptor interactor 12)
Heterocephalus glaber (naked mole-rat) : Trip12 (thyroid hormone receptor interactor 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0992,305,059 - 92,435,388 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl992,305,051 - 92,435,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0992,038,603 - 92,167,963 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4983,961,411 - 84,085,077 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1984,145,673 - 84,268,469 (-)NCBI
Celera983,343,045 - 83,465,833 (-)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Trip12
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306607
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.