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Gene: Mcm5 (minichromosome maintenance complex component 5) Rattus norvegicus
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Symbol: Mcm5
Name: minichromosome maintenance complex component 5
Description: Predicted to contribute to 3'-5' DNA helicase activity and single-stranded DNA helicase activity. Predicted to be involved in DNA replication initiation; double-strand break repair via break-induced replication; and pre-replicative complex assembly involved in nuclear cell cycle DNA replication. Predicted to localize to the MCM complex and nucleoplasm. Biomarker of alcohol use disorder. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 8. Orthologous to human MCM5 (minichromosome maintenance complex component 5); PARTICIPATES IN cell cycle pathway, mitotic; DNA replication pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA replication licensing factor MCM5; LOC291885; minichromosome maintenance deficient 5, cell division cycle 46; minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
Orthologs:
Homo sapiens (human) : MCM5 (minichromosome maintenance complex component 5)  HGNC  Alliance
Mus musculus (house mouse) : Mcm5 (minichromosome maintenance complex component 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcm5 (minichromosome maintenance complex component 5)
Pan paniscus (bonobo/pygmy chimpanzee) : MCM5 (minichromosome maintenance complex component 5)
Canis lupus familiaris (dog) : MCM5 (minichromosome maintenance complex component 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcm5 (minichromosome maintenance complex component 5)
Sus scrofa (pig) : MCM5 (minichromosome maintenance complex component 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01914,523,482 - 14,561,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01925,637,492 - 25,681,915 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41913,978,940 - 14,000,641 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11913,983,526 - 14,004,713 (+)NCBI
Celera1913,350,043 - 13,370,664 (+)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mcm5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306616
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.