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Gene: Fis1 (fission, mitochondrial 1) Rattus norvegicus
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Symbol: Fis1
Name: fission, mitochondrial 1
Description: Predicted to have signaling receptor binding activity. Involved in several processes, including cellular response to thapsigargin; mitochondrial fragmentation involved in apoptotic process; and positive regulation of mitochondrial fission. Localizes to the integral component of mitochondrial outer membrane and peroxisomal membrane. Biomarker of dental fluorosis; fatty liver disease; kidney failure (multiple); myocardial infarction; and rhinitis. Orthologous to human FIS1 (fission, mitochondrial 1); PARTICIPATES IN mitochondria fission pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; 4-DAMP(1+); aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: fis1 homolog; fission 1 (mitochondrial outer membrane) homolog; fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); fission 1 (mitochondrial outer membrane) homolog (yeast); LOC288584; mitochondrial fission 1 protein; rFis1; tetratricopeptide repeat domain 11; tetratricopeptide repeat protein 11; TPR repeat protein 11; Ttc11
Orthologs:
Homo sapiens (human) : FIS1 (fission, mitochondrial 1)  HGNC  Alliance
Mus musculus (house mouse) : Fis1 (fission, mitochondrial 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fis1 (fission, mitochondrial 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FIS1 (fission, mitochondrial 1)
Canis lupus familiaris (dog) : FIS1 (fission, mitochondrial 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fis1 (fission, mitochondrial 1)
Sus scrofa (pig) : FIS1 (fission, mitochondrial 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01222,750,485 - 22,765,324 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01224,760,051 - 24,774,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41220,806,840 - 20,821,766 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11220,807,273 - 20,811,373 (+)NCBI
Celera1221,483,983 - 21,498,749 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fis1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306668
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.