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Gene: Prickle2 (prickle planar cell polarity protein 2) Rattus norvegicus
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Symbol: Prickle2
Name: prickle planar cell polarity protein 2
Description: Predicted to have zinc ion binding activity. Predicted to be involved in several processes, including establishment of cell polarity; establishment or maintenance of epithelial cell apical/basal polarity; and trophectodermal cell fate commitment. Predicted to localize to several cellular components, including the apicolateral plasma membrane; lateral plasma membrane; and nucleus. Orthologous to human PRICKLE2 (prickle planar cell polarity protein 2); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; Wnt signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC312563; prickle homolog 2; prickle homolog 2 (Drosophila); prickle-like 2; prickle-like 2 (Drosophila) ; prickle-like protein 2
Orthologs:
Homo sapiens (human) : PRICKLE2 (prickle planar cell polarity protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Prickle2 (prickle planar cell polarity protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prickle2 (prickle planar cell polarity protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRICKLE2 (prickle planar cell polarity protein 2)
Canis lupus familiaris (dog) : PRICKLE2 (prickle planar cell polarity protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prickle2 (prickle planar cell polarity protein 2)
Sus scrofa (pig) : PRICKLE2 (prickle planar cell polarity protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04124,238,167 - 124,584,176 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04188,680,318 - 189,025,114 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,571,461 - 126,920,730 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14126,820,833 - 126,938,959 (-)NCBI
Celera4113,786,958 - 114,131,482 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Prickle2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306723
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.