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Gene: Dennd5a (DENN domain containing 5A) Rattus norvegicus
Symbol: Dennd5a
Name: DENN domain containing 5A
Description: Predicted to have Rab guanyl-nucleotide exchange factor activity. Involved in negative regulation of neuron projection development. Predicted to colocalize with the retromer complex. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 49. Orthologous to human DENND5A (DENN domain containing 5A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DENN domain-containing protein 5A; DENN/MADD domain containing 5A; LOC308942; Rab6 interacting protein 1; Rab6ip1
Homo sapiens (human) : DENND5A (DENN domain containing 5A)  HGNC  Alliance
Mus musculus (house mouse) : Dennd5a (DENN/MADD domain containing 5A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dennd5a (DENN domain containing 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : DENND5A (DENN domain containing 5A)
Canis lupus familiaris (dog) : DENND5A (DENN domain containing 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dennd5a (DENN domain containing 5A)
Sus scrofa (pig) : DENND5A (DENN domain containing 5A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01174,524,047 - 174,588,553 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01181,508,456 - 181,572,964 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,519,644 - 167,586,964 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11167,630,306 - 167,697,627 (-)NCBI
Celera1161,826,111 - 161,891,772 (-)NCBICelera
Cytogenetic Map1q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Dennd5a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306759
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.