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Gene: Dna2 (DNA replication helicase/nuclease 2) Rattus norvegicus
Symbol: Dna2
Name: DNA replication helicase/nuclease 2
Description: ENCODES a protein that exhibits 5'-3' DNA helicase activity (ortholog); 5'-flap endonuclease activity (ortholog); DNA binding (ortholog); INVOLVED IN DNA double-strand break processing (ortholog); DNA replication (ortholog); DNA replication checkpoint (ortholog); PARTICIPATES IN homologous recombination pathway of double-strand break repair; DNA replication pathway; ASSOCIATED WITH isolated growth hormone deficiency type IA (ortholog); mitochondrial myopathy (ortholog); FOUND IN gamma DNA polymerase complex (inferred); integral component of membrane (inferred); mitochondrial inner membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A
Type: protein-coding
Also known as: DNA replication ATP-dependent helicase-like homolog; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication helicase 2 homolog; DNA replication helicase 2 homolog (yeast); DNA2 DNA replication helicase 2-like; DNA2 DNA replication helicase 2-like (yeast); DNA2-like helicase; Dna2l; LOC309762; similar to DNA2 DNA replication helicase 2-like
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_5.02029,093,620 - 29,123,086 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42025,288,326 - 25,316,851 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12025,302,172 - 25,363,960 (+)NCBI
Celera2026,956,734 - 26,986,153 (-)NCBICelera
Cytogenetic Map20p11NCBI

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated


Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dna2
Alliance Gene
Ensembl Gene
JBrowse: rn5
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306791
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.