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Gene: Xrcc3 (X-ray repair cross complementing 3) Rattus norvegicus
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Symbol: Xrcc3
Name: X-ray repair cross complementing 3
Description: Predicted to contribute to crossover junction endodeoxyribonuclease activity and four-way junction DNA binding activity. Involved in response to organic substance. Predicted to localize to several cellular components, including nucleus; perinuclear region of cytoplasm; and replication fork. Human ortholog(s) of this gene implicated in breast cancer; familial melanoma; and pancreatic cancer. Orthologous to human XRCC3 (X-ray repair cross complementing 3); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH (+)-pilocarpine; amphetamine; chloroethene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA repair protein XRCC3; DNA repair protein XRCC3-like; LOC100359601; LOC102551085; LOC314463; rCG27697-like; X-ray repair complementing defective repair in Chinese hamster cells 3
Orthologs:
Homo sapiens (human) : XRCC3 (X-ray repair cross complementing 3)  HGNC  Alliance
Mus musculus (house mouse) : Xrcc3 (X-ray repair complementing defective repair in Chinese hamster cells 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrcc3 (X-ray repair cross complementing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : XRCC3 (X-ray repair cross complementing 3)
Canis lupus familiaris (dog) : XRCC3 (X-ray repair cross complementing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrcc3 (X-ray repair cross complementing 3)
Sus scrofa (pig) : XRCC3 (X-ray repair cross complementing 3)
Chlorocebus sabaeus (African green monkey) : XRCC3 (X-ray repair cross complementing 3)
Heterocephalus glaber (naked mole-rat) : Xrcc3 (X-ray repair cross complementing 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06136,366,917 - 136,380,751 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,371,555 - 136,379,348 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06145,372,463 - 145,388,673 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,594,276 - 136,602,069 (-)NCBIRGSC3.4rn4RGSC3.4
Celera6128,413,783 - 128,427,617 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Xrcc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306849
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.