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Gene: Mlf1 (myeloid leukemia factor 1) Rattus norvegicus
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Symbol: Mlf1
Name: myeloid leukemia factor 1
Description: Predicted to have DNA binding activity and protein domain specific binding activity. Predicted to be involved in several processes, including cell cycle arrest; myeloid progenitor cell differentiation; and transcription, DNA-templated. Predicted to localize to several cellular components, including the ciliary basal body; ciliary base; and non-motile cilium. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human MLF1 (myeloid leukemia factor 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC310483
Orthologs:
Homo sapiens (human) : MLF1 (myeloid leukemia factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Mlf1 (myeloid leukemia factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mlf1 (myeloid leukemia factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MLF1 (myeloid leukemia factor 1)
Canis lupus familiaris (dog) : MLF1 (myeloid leukemia factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mlf1 (myeloid leukemia factor 1)
Sus scrofa (pig) : MLF1 (myeloid leukemia factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02164,549,423 - 164,582,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02183,898,731 - 183,931,974 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42157,230,783 - 157,263,847 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12157,180,790 - 157,213,807 (+)NCBI
Celera2146,019,001 - 146,051,756 (+)NCBICelera
Cytogenetic Map2q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mlf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306854
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.