Gene: Prox1 (prospero homeobox 1) Rattus norvegicus
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Symbol: Prox1
Name: prospero homeobox 1
Description: Predicted to have several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and protein domain specific binding activity; involved in brain development, liver development, and response to nutrient levels; localizes to the nucleus; biomarker of status epilepticus; orthologous to human PROX1 (prospero homeobox 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: prospero homeobox protein 1; prospero-related homeobox 1
Orthologs:
Homo sapiens (human) : PROX1 (prospero homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Prox1 (prospero homeobox 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prox1 (prospero homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PROX1 (prospero homeobox 1)
Canis lupus familiaris (dog) : PROX1 (prospero homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prox1 (prospero homeobox 1)
Sus scrofa (pig) : PROX1 (prospero homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013108,382,536 - 108,444,107 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013113,004,568 - 113,064,606 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413106,421,541 - 106,471,350 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113106,611,772 - 106,660,015 (-)NCBI
Celera13101,149,597 - 101,200,064 (-)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Prox1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306890
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.