Gene: Arhgef15 (Rho guanine nucleotide exchange factor 15) Rattus norvegicus
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Symbol: Arhgef15
Name: Rho guanine nucleotide exchange factor 15
Description: Exhibits Rho guanyl-nucleotide exchange factor activity; involved in positive regulation of stress fiber assembly and regulation of catalytic activity; localizes to the cytoplasm; orthologous to human ARHGEF15 (Rho guanine nucleotide exchange factor 15); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,6-dinitrotoluene; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E5; ephexin-5; LOC287418; Rho guanine nucleotide exchange factor (GEF) 15
Orthologs:
Homo sapiens (human) : ARHGEF15 (Rho guanine nucleotide exchange factor 15)  HGNC  Alliance
Mus musculus (house mouse) : Arhgef15 (Rho guanine nucleotide exchange factor (GEF) 15)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef15 (Rho guanine nucleotide exchange factor 15)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF15 (Rho guanine nucleotide exchange factor 15)
Canis lupus familiaris (dog) : ARHGEF15 (Rho guanine nucleotide exchange factor 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef15 (Rho guanine nucleotide exchange factor 15)
Sus scrofa (pig) : ARHGEF15 (Rho guanine nucleotide exchange factor 15)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01055,532,097 - 55,545,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01055,274,558 - 55,288,124 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,703,919 - 55,716,219 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11055,719,072 - 55,729,109 (-)NCBI
Celera1052,816,914 - 52,829,189 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Arhgef15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306961
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.