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Gene: Cfl2 (cofilin 2) Rattus norvegicus
Symbol: Cfl2
Name: cofilin 2
CRRD ID: 1306982
Description: Predicted to have actin filament binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; muscle cell cellular homeostasis; and positive regulation of actin filament depolymerization. Predicted to localize to Z disc and actin cytoskeleton. Human ortholog(s) of this gene implicated in nemaline myopathy 7. Orthologous to human CFL2 (cofilin 2); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cofilin 2, muscle; cofilin-2; LOC366624
Homo sapiens (human) : CFL2 (cofilin 2)  HGNC  Alliance
Mus musculus (house mouse) : Cfl2 (cofilin 2, muscle)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cfl2 (cofilin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CFL2 (cofilin 2)
Canis lupus familiaris (dog) : CFL2 (cofilin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cfl2 (cofilin 2)
Sus scrofa (pig) : CFL2 (cofilin 2)
Chlorocebus sabaeus (African green monkey) : CFL2 (cofilin 2)
Heterocephalus glaber (naked mole-rat) : Cfl2 (cofilin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0675,759,140 - 75,763,185 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,759,140 - 75,763,185 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0685,300,272 - 85,304,317 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4675,203,408 - 75,207,425 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1675,206,505 - 75,210,540 (-)NCBI
Celera671,199,891 - 71,203,936 (-)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Cfl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306982
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.