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Gene: Cfl2 (cofilin 2) Rattus norvegicus
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Symbol: Cfl2
Name: cofilin 2
Description: Predicted to have actin filament binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; muscle cell cellular homeostasis; and positive regulation of actin filament depolymerization. Predicted to localize to the Z disc. Human ortholog(s) of this gene implicated in nemaline myopathy 7. Orthologous to human CFL2 (cofilin 2); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cofilin 2, muscle; cofilin-2; LOC366624
Orthologs:
Homo sapiens (human) : CFL2 (cofilin 2)  HGNC  Alliance
Mus musculus (house mouse) : Cfl2 (cofilin 2, muscle)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cfl2 (cofilin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CFL2 (cofilin 2)
Canis lupus familiaris (dog) : CFL2 (cofilin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cfl2 (cofilin 2)
Sus scrofa (pig) : CFL2 (cofilin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0675,759,140 - 75,763,185 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0685,300,272 - 85,304,317 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4675,203,408 - 75,207,425 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1675,206,505 - 75,210,540 (-)NCBI
Celera671,199,891 - 71,203,936 (-)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cfl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1306982
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.