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Gene: Aspm (assembly factor for spindle microtubules) Rattus norvegicus
Symbol: Aspm
Name: assembly factor for spindle microtubules
Description: Predicted to have calmodulin binding activity. Predicted to be involved in several processes, including gamete generation; maintenance of centrosome location; and nervous system development. Localizes to apical plasma membrane; microtubule cytoskeleton; and midbody. Human ortholog(s) of this gene implicated in microcephaly; primary autosomal recessive microcephaly; primary autosomal recessive microcephaly 5; and visual epilepsy. Orthologous to human ASPM (assembly factor for spindle microtubules); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: abnormal spindle microtubule assembly; asp (abnormal spindle) homolog, microcephaly associated; asp (abnormal spindle) homolog, microcephaly associated (Drosophila); asp (abnormal spindle)-like, microcephaly associated; asp (abnormal spindle)-like, microcephaly associated (Drosophila) ; Calmbp1; calmodulin binding protein 1; LOC289054
Homo sapiens (human) : ASPM (assembly factor for spindle microtubules)  HGNC  Alliance
Mus musculus (house mouse) : Aspm (abnormal spindle microtubule assembly)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aspm (assembly factor for spindle microtubules)
Pan paniscus (bonobo/pygmy chimpanzee) : ASPM (assembly factor for spindle microtubules)
Canis lupus familiaris (dog) : ASPM (assembly factor for spindle microtubules)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aspm (assembly factor for spindle microtubules)
Sus scrofa (pig) : ASPM (assembly factor for spindle microtubules)
Chlorocebus sabaeus (African green monkey) : ASPM (assembly factor for spindle microtubules)
Heterocephalus glaber (naked mole-rat) : Aspm (assembly factor for spindle microtubules)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01356,546,021 - 56,591,793 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1356,546,021 - 56,591,793 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01361,564,059 - 61,609,831 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41352,811,658 - 52,860,925 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11352,825,867 - 52,874,707 (+)NCBI
Celera1351,338,709 - 51,386,444 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Aspm
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307111
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.