Gene: Lias (lipoic acid synthetase) Rattus norvegicus
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Symbol: Lias
Name: lipoic acid synthetase
Description: Predicted to have lipoate synthase activity. Predicted to be involved in several processes, including lipoate biosynthetic process; protein lipoylation; and response to lipopolysaccharide. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human LIAS (lipoic acid synthetase); PARTICIPATES IN lipoic acid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: lip-syn; lipoate synthase; lipoic acid synthase; lipoyl synthase, mitochondrial; LOC305348; LS
Orthologs:
Homo sapiens (human) : LIAS (lipoic acid synthetase)  HGNC  Alliance
Mus musculus (house mouse) : Lias (lipoic acid synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lias (lipoic acid synthetase)
Pan paniscus (bonobo/pygmy chimpanzee) : LIAS (lipoic acid synthetase)
Canis lupus familiaris (dog) : LIAS (lipoic acid synthetase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lias (lipoic acid synthetase)
Sus scrofa (pig) : LIAS (lipoic acid synthetase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01444,507,217 - 44,524,287 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01444,326,598 - 44,343,665 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,575,334 - 45,592,514 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11445,577,725 - 45,594,905 (-)NCBI
Celera1442,027,393 - 42,044,418 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lias
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307270
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.