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Gene: Zeb2 (zinc finger E-box binding homeobox 2) Rattus norvegicus
Symbol: Zeb2
Name: zinc finger E-box binding homeobox 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; R-SMAD binding activity; and sequence-specific DNA binding activity. Predicted to be involved in several processes, including ameboidal-type cell migration; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to localize to cytosol and nuclear lumen. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
Also known as: LOC311071; Zfhx1b; zinc finger E-box-binding homeobox 2; zinc finger homeobox 1b
Homo sapiens (human) : ZEB2 (zinc finger E-box binding homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Zeb2 (zinc finger E-box binding homeobox 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zeb2 (zinc finger E-box binding homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZEB2 (zinc finger E-box binding homeobox 2)
Canis lupus familiaris (dog) : ZEB2 (zinc finger E-box binding homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zeb2 (zinc finger E-box binding homeobox 2)
Sus scrofa (pig) : ZEB2 (zinc finger E-box binding homeobox 2)
Chlorocebus sabaeus (African green monkey) : ZEB2 (zinc finger E-box binding homeobox 2)
Heterocephalus glaber (naked mole-rat) : Zeb2 (zinc finger E-box binding homeobox 2)
more info ...
Is Marker For: Strains:   F344-Zeb2em1Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0329,857,289 - 29,985,932 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl329,862,473 - 29,996,865 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0335,058,725 - 35,186,767 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4325,513,009 - 25,654,964 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1325,409,380 - 25,556,869 (-)NCBI
Celera327,525,557 - 27,647,939 (-)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Zeb2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307272
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.