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Gene: Zeb2 (zinc finger E-box binding homeobox 2) Rattus norvegicus
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Symbol: Zeb2
Name: zinc finger E-box binding homeobox 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; R-SMAD binding activity; and sequence-specific DNA binding activity. Predicted to be involved in several processes, including ameboidal-type cell migration; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to localize to cytosol and nuclear lumen. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC311071; Zfhx1b; zinc finger E-box-binding homeobox 2; zinc finger homeobox 1b
Orthologs:
Homo sapiens (human) : ZEB2 (zinc finger E-box binding homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Zeb2 (zinc finger E-box binding homeobox 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zeb2 (zinc finger E-box binding homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZEB2 (zinc finger E-box binding homeobox 2)
Canis lupus familiaris (dog) : ZEB2 (zinc finger E-box binding homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zeb2 (zinc finger E-box binding homeobox 2)
Sus scrofa (pig) : ZEB2 (zinc finger E-box binding homeobox 2)
Chlorocebus sabaeus (African green monkey) : ZEB2 (zinc finger E-box binding homeobox 2)
Heterocephalus glaber (naked mole-rat) : Zeb2 (zinc finger E-box binding homeobox 2)
more info ...
Is Marker For: Strains:   F344-Zeb2em1Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0329,857,289 - 29,985,932 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl329,862,473 - 29,996,865 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0335,058,725 - 35,186,767 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4325,513,009 - 25,654,964 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1325,409,380 - 25,556,869 (-)NCBI
Celera327,525,557 - 27,647,939 (-)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Zeb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307272
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.