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Gene: Aim2 (absent in melanoma 2) Rattus norvegicus
Symbol: Aim2
Name: absent in melanoma 2
Description: Predicted to have double-stranded DNA binding activity and identical protein binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; protein-containing complex assembly; and regulation of DNA-binding transcription factor activity. Predicted to localize to AIM2 inflammasome complex; mitochondrion; and nucleoplasm. Orthologous to human AIM2 (absent in melanoma 2); PARTICIPATES IN interleukin-1 signaling pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: MODEL
Also known as: interferon-inducible protein AIM2; LOC304987
Homo sapiens (human) : AIM2 (absent in melanoma 2)  HGNC  Alliance
Mus musculus (house mouse) : Aim2 (absent in melanoma 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : AIM2 (absent in melanoma 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aim2 (absent in melanoma 2)
Chlorocebus sabaeus (African green monkey) : AIM2 (absent in melanoma 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01391,919,834 - 91,963,080 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,954,138 - 91,962,588 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01396,436,637 - 96,478,372 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41389,631,797 - 89,640,265 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11389,820,680 - 89,826,398 (+)NCBI
Celera1385,466,773 - 85,510,053 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Aim2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307283
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.