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Gene: Wnk2 (WNK lysine deficient protein kinase 2) Rattus norvegicus
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Symbol: Wnk2
Name: WNK lysine deficient protein kinase 2
Description: Predicted to have chloride channel inhibitor activity; potassium channel inhibitor activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including protein autophosphorylation; regulation of metal ion transport; and regulation of signal transduction. Predicted to localize to the cytosol. Biomarker of transient cerebral ischemia. Orthologous to human WNK2 (WNK lysine deficient protein kinase 2); INTERACTS WITH 17beta-estradiol; bisphenol A; nitrofen.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: kinase deficient protein; LOC306811; RGD1307284; serine/threonine-protein kinase WNK2; similar to protein kinase, lysine deficient 1
Orthologs:
Homo sapiens (human) : WNK2 (WNK lysine deficient protein kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Wnk2 (WNK lysine deficient protein kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnk2 (WNK lysine deficient protein kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : WNK2 (WNK lysine deficient protein kinase 2)
Canis lupus familiaris (dog) : WNK2 (WNK lysine deficient protein kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnk2 (WNK lysine deficient protein kinase 2)
Sus scrofa (pig) : WNK2 (WNK lysine deficient protein kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01715,923,508 - 16,032,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01717,986,985 - 18,095,251 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41721,461,980 - 21,600,361 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11721,462,134 - 21,600,354 (+)NCBI
Celera1715,234,024 - 15,342,287 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Wnk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307284
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-05-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.