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Gene: Sesn1 (sestrin 1) Rattus norvegicus
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Symbol: Sesn1
Name: sestrin 1
Description: Predicted to have leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Predicted to be involved in several processes, including cellular response to leucine; cellular response to starvation; and regulation of intracellular signal transduction. Predicted to colocalize with the GATOR2 complex; TORC2 complex; and cytoplasm. Orthologous to human SESN1 (sestrin 1); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH (RS)-amphetamine; (S)-colchicine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC294518; sestrin-1
Orthologs:
Homo sapiens (human) : SESN1 (sestrin 1)  HGNC  Alliance
Mus musculus (house mouse) : Sesn1 (sestrin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sesn1 (sestrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SESN1 (sestrin 1)
Canis lupus familiaris (dog) : SESN1 (sestrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sesn1 (sestrin 1)
Sus scrofa (pig) : SESN1 (sestrin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02046,667,116 - 46,758,306 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02048,347,213 - 48,437,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42045,786,623 - 45,877,856 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12045,879,708 - 45,900,868 (+)NCBI
Celera2054,572,050 - 54,662,230 (-)NCBICelera
Cytogenetic Map20q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sesn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307517
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.