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Gene: Hexb (hexosaminidase subunit beta) Rattus norvegicus
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Symbol: Hexb
Name: hexosaminidase subunit beta
Description: Exhibits beta-N-acetylglucosaminidase activity; carbohydrate binding activity; and protein dimerization activity. Involved in N-acetylglucosamine metabolic process. Localizes to the lysosome. Human ortholog(s) of this gene implicated in Sandhoff disease and spinal muscular atrophy. Orthologous to human HEXB (hexosaminidase subunit beta); PARTICIPATES IN amino sugar metabolic pathway; ganglioside metabolic pathway; globoside metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-di-tert-butyl-4-methylphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: beta-hexosaminidase subunit beta; beta-N-acetylhexosaminidase subunit beta; hexosaminidase B; hexosaminidase subunit B; LOC294673; N-acetyl-beta-glucosaminidase subunit beta
Orthologs:
Homo sapiens (human) : HEXB (hexosaminidase subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Hexb (hexosaminidase B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hexb (hexosaminidase subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : HEXB (hexosaminidase subunit beta)
Canis lupus familiaris (dog) : HEXB (hexosaminidase subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hexb (hexosaminidase subunit beta)
Sus scrofa (pig) : HEXB (hexosaminidase subunit beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0227,983,925 - 28,003,260 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0247,094,814 - 47,114,992 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,649,188 - 27,672,231 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1227,569,557 - 27,592,600 (-)NCBI
Celera224,525,921 - 24,545,955 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hexb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307607
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.