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Gene: Drosha (drosha ribonuclease III) Rattus norvegicus
Symbol: Drosha
Name: drosha ribonuclease III
Description: Predicted to have several functions, including DEAD/H-box RNA helicase binding activity; R-SMAD binding activity; and RNA binding activity. Predicted to be involved in several processes, including defense response to bacterium; miRNA metabolic process; and production of small RNA involved in gene silencing by RNA. Predicted to localize to the microprocessor complex and postsynaptic density. Orthologous to human DROSHA (drosha ribonuclease III); PARTICIPATES IN microRNA pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: drosha, ribonuclease type III; ethanol induced 2; Etohi2; LOC310159; RGD1307626; ribonuclease 3; ribonuclease III, nuclear; ribonuclease type III, nuclear; Rn3; Rnasen; similar to Ribonuclease III (RNase III) (p241)
Homo sapiens (human) : DROSHA (drosha ribonuclease III)  HGNC  Alliance
Mus musculus (house mouse) : Drosha (drosha, ribonuclease type III)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Drosha (drosha ribonuclease III)
Pan paniscus (bonobo/pygmy chimpanzee) : DROSHA (drosha ribonuclease III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Drosha (drosha ribonuclease III)
Sus scrofa (pig) : DROSHA (drosha ribonuclease III)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0262,887,267 - 63,000,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0281,692,120 - 81,804,978 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4262,336,007 - 62,447,618 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1262,264,382 - 62,375,798 (+)NCBI
Celera256,722,605 - 56,834,195 (-)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Drosha
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307626
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.