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Gene: Drosha (drosha ribonuclease III) Rattus norvegicus
Symbol: Drosha
Name: drosha ribonuclease III
Description: Predicted to have several functions, including DEAD/H-box RNA helicase binding activity; R-SMAD binding activity; and RNA binding activity. Predicted to be involved in several processes, including defense response to bacterium; production of small RNA involved in gene silencing by RNA; and regulation of regulatory T cell differentiation. Predicted to localize to microprocessor complex and postsynaptic density. Orthologous to human DROSHA (drosha ribonuclease III); PARTICIPATES IN microRNA pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: drosha, ribonuclease type III; ethanol induced 2; Etohi2; LOC310159; RGD1307626; ribonuclease 3; ribonuclease III, nuclear; ribonuclease type III, nuclear; Rn3; Rnasen; similar to Ribonuclease III (RNase III) (p241)
Homo sapiens (human) : DROSHA (drosha ribonuclease III)  HGNC  Alliance
Mus musculus (house mouse) : Drosha (drosha, ribonuclease type III)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Drosha (drosha ribonuclease III)
Pan paniscus (bonobo/pygmy chimpanzee) : DROSHA (drosha ribonuclease III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Drosha (drosha ribonuclease III)
Sus scrofa (pig) : DROSHA (drosha ribonuclease III)
Chlorocebus sabaeus (African green monkey) : DROSHA (drosha ribonuclease III)
Heterocephalus glaber (naked mole-rat) : Drosha (drosha ribonuclease III)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0262,887,267 - 63,000,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl262,887,267 - 62,999,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0281,692,120 - 81,804,978 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4262,336,007 - 62,447,618 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1262,264,382 - 62,375,798 (+)NCBI
Celera256,722,605 - 56,834,195 (-)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Drosha
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307626
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.