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Gene: Nfatc2 (nuclear factor of activated T-cells 2) Rattus norvegicus
Symbol: Nfatc2
Name: nuclear factor of activated T-cells 2
Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and phosphatase binding activity. Predicted to be involved in several processes, including calcineurin-NFAT signaling cascade; regulation of muscle cell differentiation; and regulation of transcription by RNA polymerase II. Localizes to the cytosol and nucleus. Used to study pulmonary hypertension. Orthologous to human NFATC2 (nuclear factor of activated T cells 2); PARTICIPATES IN calcineurin signaling pathway; nuclear factor of activated T-cells signaling pathway; Wnt signaling, non-canonical pathway; INTERACTS WITH amphetamine; copper atom; copper(0).
Type: protein-coding
Also known as: LOC311658; nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
Homo sapiens (human) : NFATC2 (nuclear factor of activated T cells 2)  HGNC  Alliance
Mus musculus (house mouse) : Nfatc2 (nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfatc2 (nuclear factor of activated T cells 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NFATC2 (nuclear factor of activated T cells 2)
Canis lupus familiaris (dog) : NFATC2 (nuclear factor of activated T cells 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfatc2 (nuclear factor of activated T cells 2)
Sus scrofa (pig) : NFATC2 (nuclear factor of activated T cells 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03165,241,750 - 165,374,644 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3165,245,238 - 165,360,292 (-)Ensembl
Rnor_5.03171,380,993 - 171,514,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,656,032 - 159,773,643 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13159,560,378 - 159,679,702 (-)NCBI
Celera3155,769,159 - 155,882,096 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nfatc2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307690
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.