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Gene: Tbx6 (T-box transcription factor 6) Rattus norvegicus
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Symbol: Tbx6
Name: T-box transcription factor 6
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in several processes, including embryonic morphogenesis; negative regulation of neuron differentiation; and regulation of transcription, DNA-templated. Predicted to localize to nuclear chromatin. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human TBX6 (T-box transcription factor 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC365371; T-box 6; T-box protein 6; T-box transcription factor TBX6
Orthologs:
Homo sapiens (human) : TBX6 (T-box transcription factor 6)  HGNC  Alliance
Mus musculus (house mouse) : Tbx6 (T-box 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx6 (T-box transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX6 (T-box transcription factor 6)
Canis lupus familiaris (dog) : TBX6 (T-box transcription factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx6 (T-box transcription factor 6)
Sus scrofa (pig) : TBX6 (T-box transcription factor 6)
Chlorocebus sabaeus (African green monkey) : TBX6 (T-box transcription factor 6)
Heterocephalus glaber (naked mole-rat) : Tbx6 (T-box transcription factor 6)
more info ...
Is Marker For: Strains:   F344-Oune/Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01198,214,797 - 198,218,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,214,797 - 198,218,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,194,665 - 205,198,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,957,068 - 185,960,977 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,106,948 - 186,110,858 (+)NCBI
Celera1179,044,203 - 179,048,112 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tbx6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307716
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.