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Gene: Nsd1 (nuclear receptor binding SET domain protein 1) Rattus norvegicus
Symbol: Nsd1
Name: nuclear receptor binding SET domain protein 1
Description: Predicted to have several functions, including histone-lysine N-methyltransferase activity; nuclear hormone receptor binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including regulation of RNA polymerase II regulatory region sequence-specific DNA binding activity; regulation of protein modification process; and regulation of transcription, DNA-templated. Predicted to localize to chromatin and nucleus. Human ortholog(s) of this gene implicated in Sotos syndrome; acute myeloid leukemia; microcephaly; and neuroblastoma. Orthologous to human NSD1 (nuclear receptor binding SET domain protein 1); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A.
Type: protein-coding
Also known as: histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; LOC306764
Homo sapiens (human) : NSD1 (nuclear receptor binding SET domain protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Nsd1 (nuclear receptor-binding SET-domain protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nsd1 (nuclear receptor binding SET domain protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NSD1 (nuclear receptor binding SET domain protein 1)
Canis lupus familiaris (dog) : NSD1 (nuclear receptor binding SET domain protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nsd1 (nuclear receptor binding SET domain protein 1)
Sus scrofa (pig) : NSD1 (nuclear receptor binding SET domain protein 1)
Chlorocebus sabaeus (African green monkey) : NSD1 (nuclear receptor binding SET domain protein 1)
Heterocephalus glaber (naked mole-rat) : Nsd1 (nuclear receptor binding SET domain protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0179,840,859 - 9,955,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,844,133 - 9,952,898 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,950,539 - 12,065,042 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,362,482 - 15,471,961 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11715,363,376 - 15,471,151 (-)NCBI
Celera179,393,607 - 9,502,492 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nsd1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307748
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.