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Gene: Aprt (adenine phosphoribosyl transferase) Rattus norvegicus
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Symbol: Aprt
Name: adenine phosphoribosyl transferase
Description: Exhibits AMP binding activity. Involved in cellular response to insulin stimulus and lactation. Predicted to localize to the cytosol and nucleoplasm. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in adenine phosphoribosyltransferase deficiency. Orthologous to human APRT (adenine phosphoribosyltransferase); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 2,6-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adenine phosphoribosyltransferase; LOC292072
Orthologs:
Homo sapiens (human) : APRT (adenine phosphoribosyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Aprt (adenine phosphoribosyl transferase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aprt (adenine phosphoribosyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : APRT (adenine phosphoribosyltransferase)
Canis lupus familiaris (dog) : APRT (adenine phosphoribosyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aprt (adenine phosphoribosyltransferase)
Sus scrofa (pig) : APRT (adenine phosphoribosyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01955,387,288 - 55,389,256 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01966,095,804 - 66,097,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,854,657 - 52,856,625 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,859,538 - 52,861,506 (-)NCBI
Celera1949,865,842 - 49,867,810 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Aprt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307758
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.