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Gene: Irf7 (interferon regulatory factor 7) Rattus norvegicus
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Symbol: Irf7
Name: interferon regulatory factor 7
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and enhancer sequence-specific DNA binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of type I interferon production; and regulation of innate immune response. Predicted to localize to the cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human IRF7 (interferon regulatory factor 7); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC293624; MGC125013
Orthologs:
Homo sapiens (human) : IRF7 (interferon regulatory factor 7)  HGNC  Alliance
Mus musculus (house mouse) : Irf7 (interferon regulatory factor 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irf7 (interferon regulatory factor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : IRF7 (interferon regulatory factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irf7 (interferon regulatory factor 7)
Sus scrofa (pig) : IRF7 (interferon regulatory factor 7)
Chlorocebus sabaeus (African green monkey) : IRF7 (interferon regulatory factor 7)
Heterocephalus glaber (naked mole-rat) : Irf7 (interferon regulatory factor 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01214,249,388 - 214,252,909 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,248,837 - 214,252,456 (-)Ensembl
Rnor_5.01221,166,926 - 221,170,447 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,456,689 - 201,459,756 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11201,607,693 - 201,611,125 (-)NCBI
Celera1194,001,244 - 194,004,312 (-)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Irf7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307828
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.