Gene: Pias1 (protein inhibitor of activated STAT, 1) Rattus norvegicus
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Symbol: Pias1
Name: protein inhibitor of activated STAT, 1
Description: Exhibits SUMO transferase activity, protein C-terminus binding activity, and protein domain specific binding activity; involved in several processes, including G1/S transition of mitotic cell cycle, negative regulation of apoptotic process, and positive regulation of cellular metabolic process; localizes to the nucleus; predicted to colocalize with the PML body; biomarker of focal segmental glomerulosclerosis; orthologous to human PIAS1 (protein inhibitor of activated STAT 1); PARTICIPATES IN aldosterone signaling pathway; ataxia telangiectasia-mutated (ATM) signaling pathway; Hedgehog signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 SUMO-protein ligase PIAS1; LOC300772; protein inhibitor of activated STAT 1
Orthologs:
Homo sapiens (human) : PIAS1 (protein inhibitor of activated STAT 1)  HGNC  Alliance
Mus musculus (house mouse) : Pias1 (protein inhibitor of activated STAT 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias1 (protein inhibitor of activated STAT 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS1 (protein inhibitor of activated STAT 1)
Canis lupus familiaris (dog) : PIAS1 (protein inhibitor of activated STAT 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias1 (protein inhibitor of activated STAT 1)
Sus scrofa (pig) : PIAS1 (protein inhibitor of activated STAT 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0867,771,720 - 67,869,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0867,500,467 - 67,597,762 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4867,025,248 - 67,123,016 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1867,044,301 - 67,142,058 (-)NCBI
Celera862,756,508 - 62,854,013 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pias1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307843
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.