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Gene: Prex2 (phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2) Rattus norvegicus
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Symbol: Prex2
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Description: Predicted to have GTPase activator activity and Rac guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including adult locomotory behavior; dendrite morphogenesis; and phosphatidylinositol 3-kinase signaling. Predicted to localize to the plasma membrane. Orthologous to human PREX2 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DEP domain containing 2; Depdc2; LOC312912; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.057,622,668 - 7,941,715 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0512,446,043 - 12,761,369 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.457,404,475 - 7,693,459 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.157,366,703 - 7,728,758 (-)NCBI
Celera57,493,673 - 7,724,174 (-)NCBICelera
Cytogenetic Map5q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Prex2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307865
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.