Gene: Twnk (twinkle mtDNA helicase) Rattus norvegicus
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Symbol: Twnk
Name: twinkle mtDNA helicase
Description: Predicted to have 5'-3' DNA helicase activity, protease binding activity, and single-stranded DNA binding activity; involved in cellular response to glucose stimulus; localizes to the mitochondrion; orthologous to human TWNK (twinkle mtDNA helicase); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC309441; Peo1; progressive external ophthalmoplegia 1; progressive external ophthalmoplegia 1 (human); progressive external ophthalmoplegia 1 homolog; progressive external ophthalmoplegia 1 homolog (human); twinkle protein, mitochondrial
Orthologs:
Homo sapiens (human) : TWNK (twinkle mtDNA helicase)  HGNC  Alliance
Mus musculus (house mouse) : Twnk (twinkle mtDNA helicase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Twnk (twinkle mtDNA helicase)
Pan paniscus (bonobo/pygmy chimpanzee) : TWNK (twinkle mtDNA helicase)
Canis lupus familiaris (dog) : TWNK (twinkle mtDNA helicase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Twnk (twinkle mtDNA helicase)
Sus scrofa (pig) : TWNK (twinkle mtDNA helicase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01264,756,060 - 264,762,892 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01272,198,895 - 272,205,288 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41250,073,350 - 250,079,743 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11250,334,625 - 250,339,475 (+)NCBI
Celera1239,679,537 - 239,685,930 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Twnk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307884
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.