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Gene: Def6 (DEF6 guanine nucleotide exchange factor) Rattus norvegicus
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Symbol: Def6
Name: DEF6 guanine nucleotide exchange factor
Description: Predicted to localize to the cell-cell junction; cytosol; and nucleoplasm. Orthologous to human DEF6 (DEF6 guanine nucleotide exchange factor); INTERACTS WITH 3,7-dihydropurine-6-thione; bisphenol A; DDT.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: differentially expressed in FDCP 6; differentially expressed in FDCP 6 homolog; differentially expressed in FDCP 6 homolog (mouse); LOC309642
Orthologs:
Homo sapiens (human) : DEF6 (DEF6 guanine nucleotide exchange factor)  HGNC  Alliance
Mus musculus (house mouse) : Def6 (differentially expressed in FDCP 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Def6 (DEF6 guanine nucleotide exchange factor)
Pan paniscus (bonobo/pygmy chimpanzee) : DEF6 (DEF6 guanine nucleotide exchange factor)
Canis lupus familiaris (dog) : DEF6 (DEF6 guanine nucleotide exchange factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Def6 (DEF6 guanine nucleotide exchange factor)
Sus scrofa (pig) : DEF6 (DEF6 guanine nucleotide exchange factor)
Chlorocebus sabaeus (African green monkey) : DEF6 (DEF6 guanine nucleotide exchange factor)
Heterocephalus glaber (naked mole-rat) : Def6 (DEF6 guanine nucleotide exchange factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0207,788,120 - 7,809,011 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl207,788,084 - 7,809,560 (+)Ensembl
Rnor_5.0209,988,008 - 10,010,102 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4206,391,694 - 6,469,830 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1206,448,811 - 6,470,576 (+)NCBI
Celera207,825,022 - 7,845,913 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Def6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1307945
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.