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Gene: Sim2 (SIM bHLH transcription factor 2) Rattus norvegicus
Symbol: Sim2
Name: SIM bHLH transcription factor 2
Description: Predicted to have DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and protein heterodimerization activity. Predicted to be involved in embryonic pattern specification; lung development; and negative regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear body. Orthologous to human SIM2 (SIM bHLH transcription factor 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; acrylamide; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC304071; single-minded 2; single-minded family bHLH transcription factor 2; single-minded homolog 2; single-minded homolog 2 (Drosophila)
Homo sapiens (human) : SIM2 (SIM bHLH transcription factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Sim2 (single-minded family bHLH transcription factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sim2 (SIM bHLH transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SIM2 (SIM bHLH transcription factor 2)
Canis lupus familiaris (dog) : SIM2 (SIM bHLH transcription factor 2)
Sus scrofa (pig) : SIM2 (SIM bHLH transcription factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01134,315,739 - 34,355,183 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01137,902,943 - 37,942,470 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41134,335,645 - 34,376,925 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11134,392,956 - 34,432,046 (+)NCBI
Celera1134,996,179 - 35,035,627 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Sim2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308016
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.