Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tp53bp1 (tumor protein p53 binding protein 1) Rattus norvegicus
Symbol: Tp53bp1
Name: tumor protein p53 binding protein 1
Description: Predicted to have several functions, including DNA binding activity; RNA polymerase II activating transcription factor binding activity; and histone binding activity. Involved in cellular response to X-ray. Localizes to the nucleus. Predicted to colocalize with the chromosome, telomeric region. Orthologous to human TP53BP1 (tumor protein p53 binding protein 1); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; non-homologous end joining pathway of double-strand break repair; INTERACTS WITH all-trans-retinoic acid; thioacetamide; (-)-epigallocatechin 3-gallate (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC296099; transformation related protein 53 binding protein 1; Trp53bp1; tumor suppressor p53-binding protein 1
Homo sapiens (human) : TP53BP1 (tumor protein p53 binding protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Trp53bp1 (transformation related protein 53 binding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tp53bp1 (tumor protein p53 binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TP53BP1 (tumor protein p53 binding protein 1)
Canis lupus familiaris (dog) : TP53BP1 (tumor protein p53 binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tp53bp1 (tumor protein p53 binding protein 1)
Sus scrofa (pig) : TP53BP1 (tumor protein p53 binding protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03113,160,030 - 113,259,701 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03119,697,122 - 119,799,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43107,994,425 - 108,071,133 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13107,897,216 - 107,968,850 (-)NCBI
Celera3107,073,150 - 107,144,062 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tp53bp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308039
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.