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Gene: Tnfrsf10b (tumor necrosis factor receptor superfamily, member 10b) Rattus norvegicus
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Symbol: Tnfrsf10b
Name: tumor necrosis factor receptor superfamily, member 10b
Description: Predicted to have protease binding activity and transcription factor binding activity. Involved in extrinsic apoptotic signaling pathway via death domain receptors; male gonad development; and response to organic cyclic compound. Localizes to membrane. Biomarker of colon cancer and osteoarthritis. Human ortholog(s) of this gene implicated in cervical cancer; head and neck squamous cell carcinoma; hematologic cancer (multiple); and urinary system cancer (multiple). Orthologous to human TNFRSF10A (TNF receptor superfamily member 10a); PARTICIPATES IN Trail mediated signaling pathway; apoptotic cell death pathway; influenza A pathway; INTERACTS WITH bisphenol A; (-)-epigallocatechin 3-gallate (ortholog); 1-fluoro-2,4-dinitrobenzene (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC364420
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01551,433,853 - 51,464,215 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01555,161,595 - 55,192,095 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,138,439 - 50,163,254 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11550,155,031 - 50,177,989 (+)NCBI
Celera1544,522,716 - 44,548,374 (+)NCBICelera
Cytogenetic Map15p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tnfrsf10b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308041
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.